William Blair Analysts Decrease Earnings Estimates for LYRA

Lyra Therapeutics, Inc. (NASDAQ:LYRA) – Analysts at William Blair cut their Q3 2025 EPS estimates for Lyra Therapeutics in a note issued to investors on Monday, January 20th. William Blair analyst L. Hanbury-Brown now anticipates that the company will post earnings per share of ($0.12) for the quarter, down from their previous forecast of ($0.11). The consensus estimate for Lyra Therapeutics’ current full-year earnings is ($0.93) per share. William Blair also issued estimates for Lyra Therapeutics’ Q4 2025 earnings at ($0.16) EPS and FY2025 earnings at ($0.52) EPS.

Lyra Therapeutics Stock Performance

NASDAQ LYRA opened at $0.19 on Wednesday. The firm’s 50 day moving average price is $0.19 and its two-hundred day moving average price is $0.25. Lyra Therapeutics has a twelve month low of $0.16 and a twelve month high of $6.79. The stock has a market cap of $12.60 million, a price-to-earnings ratio of -0.13 and a beta of -0.13.

Institutional Inflows and Outflows

A hedge fund recently raised its stake in Lyra Therapeutics stock. State Street Corp boosted its stake in Lyra Therapeutics, Inc. (NASDAQ:LYRA) by 88.1% in the third quarter, according to the company in its most recent filing with the Securities & Exchange Commission. The institutional investor owned 488,720 shares of the company’s stock after buying an additional 228,900 shares during the quarter. State Street Corp owned approximately 0.75% of Lyra Therapeutics worth $126,000 at the end of the most recent quarter. Hedge funds and other institutional investors own 95.62% of the company’s stock.

Lyra Therapeutics Company Profile

Lyra Therapeutics, Inc, a clinical-stage biotechnology company, focuses on the development and commercialization of novel integrated drug and delivery solutions for the localized treatment of patients with ear, nose, and throat diseases. It's XTreo technology platform is designed to deliver medicines directly to the affected tissue for sustained periods with a single administration.